MCRI Back 2 Front Clinical Data  Challenge

The Haematology team at the Murdoch Children’s Research Institute (MCRI) and Mass Dynamics (MD)
have teamed up to create a clinically relevant challenge like no other.

Run over an 8-week period, the Back 2 Front (B2F) Clinical Data challenge needs your data and science super powers to help change the way we use proteomics data to drive improved clinical approaches.
As Group Leader of the Haematology team at MCRI, Professor Vera Ignjatovic has a big vision - to disrupt the way proteomics is done and thereby improve the way in which patients are being diagnosed.

What problem is the B2F challenge addressing? Traditional proteomics projects are typically performed on predetermined groups of individuals and the differences in the proteomes between the groups are used to determine biomarkers, potential drug targets and/or to guide specific treatment protocols. That is, front-to-back.

Why we need you! This challenge is an opportunity for MCRI to explore how individuals can be segregated and classified entirely based on their proteomics data and compare unbiased crowd-sourced methods to traditional approaches. You guessed it, back-to-front.
1

Sign up, download data

Fill in our form below and follow the instructions to receive the proteomics data.
2

Classify

Predict the groupings of individuals based on their proteomic data using any or all methods, tools or existing knowledge.
3

Submit and share

Submit your results, code and methods. Tell us your thoughts and ideas!

Ready to start contributing? A few things we need to know before we get started.

Frequently asked questions.

The basics

Why was the B2F challenge created?

As Group Leader of the Haematology team at MCRI, Professor Vera Ignjatovic has a big vision - to disrupt the way proteomics is done, and thereby improve the way in which patients are being diagnosed.

Traditional proteomics projects are typically performed on predetermined groups of individuals and the differences in the proteomes between the groups are used to determine biomarkers, potential drug targets and/or to guide specific treatment protocols. That is, front-to-back.

The B2F challenge is an opportunity for MCRI to explore how individuals can be segregated and classified entirely based on their proteomics data and compare unbiased crowd-sourced methods to traditional approaches. You guess it, back-to-front.

How long does the challenge go for?

Started on Thursday February 4th 2021, this challenge will close 8 weeks later, on April 1st 2021.

How do I get started?

Firstly, complete the above Request for Data Form and we will then provide you with individual specific de-identified data which needs to be segregated and classified. By submitting us with details on the approach you used and the final composition of your groups, you will be contributing to disrupting the status-quo.

What's in it for me?

As a citizen scientist, this is an opportunity for you to develop your skills while interacting with a meaningful, real-world problem. Whether you are new to proteomics, or an expert, this is a chance to contribute your knowledge and experience to a critical task in proteomics.

Who can participate?

Anyone! We are looking for all bright minds who are willing to contribute to segregating and classifying the proteomics data. It doesn't matter what approach or tools you use.

How do I get more support?

You can email us at b2f@massdynamics.com

The Details

How do I submit my results?

You can send us your results via email (b2f@massdynamics.com), including any links required to share your results, methods and ideas.

Who owns the submissions?

All submissions are owned by you (the author of the B2F submission).

What happens with my submission?

The Haematology team at MCRI will endeavour to produce and share meaningful insights from this challenge with the scientific community and will acknowledge the contributions made by the citizen scientists.